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rarγ antagonists cd2665  (Tocris)


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    Tocris rarγ antagonists cd2665
    Rarγ Antagonists Cd2665, supplied by Tocris, used in various techniques. Bioz Stars score: 93/100, based on 24 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/rar%CE%B3+antagonists+cd2665/us11833256-356-1-12?v=Tocris
    Average 93 stars, based on 24 article reviews
    rarγ antagonists cd2665 - by Bioz Stars, 2026-08
    93/100 stars

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    rarγ antagonists cd2665  (Tocris)
    93
    Tocris rarγ antagonists cd2665
    Rarγ Antagonists Cd2665, supplied by Tocris, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/rar%CE%B3+antagonists+cd2665/us11833256-356-1-12?v=Tocris
    Average 93 stars, based on 1 article reviews
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    cd2665 (rarγ antagonists, cas 170355-78-9)  (Cayman Chemical)
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    Cayman Chemical cd2665 (rarγ antagonists, cas 170355-78-9)
    Effect of <t>RARγ</t> agonist/antagonist on ATDC5 cells and MSCs. (A) Alcian blue staining of ATDC5 cells in micromass (scale bar = 1 mm). The blue stained area was extracted using ImageJ (version 1.52q, U. S. National Institutes of Health; https://imagej.nih.gov/ij/ ) ( n = 4 per group). (B) Quantitative RT-PCR analysis of ATDC5 cells cultured in chondrogenic medium supplemented with BMP-2 (20 ng/ml) and 7C (50 nM) or NRX (100 nM) ( n = 4 per group). (C) Alcian blue staining of MSCs in micromass (scale bar = 1 mm). The blue stained area was extracted using ImageJ ( n = 4 per group). (D) The gene expression level of Sox9 in MSCs cultured in chondrogenic medium. Sox9 expression was upregulated by 7C, even in the absence of BMP-2 ( n = 3 per group). * p < 0.05, ** p < 0.01, *** p < 0.001 and **** p < 0.0001 and ns, not significant.
    Cd2665 (Rarγ Antagonists, Cas 170355 78 9), supplied by Cayman Chemical, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    cd2665 (rarγ antagonists, cas 170355-78-9) - by Bioz Stars, 2026-08
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    cd2665 (rarγ antagonists, cas 170355-78-9  (Cayman Chemical)
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    Cayman Chemical cd2665 (rarγ antagonists, cas 170355-78-9
    Effect of <t>RARγ</t> agonist/antagonist on ATDC5 cells and MSCs. (A) Alcian blue staining of ATDC5 cells in micromass (scale bar = 1 mm). The blue stained area was extracted using ImageJ (version 1.52q, U. S. National Institutes of Health; https://imagej.nih.gov/ij/ ) ( n = 4 per group). (B) Quantitative RT-PCR analysis of ATDC5 cells cultured in chondrogenic medium supplemented with BMP-2 (20 ng/ml) and 7C (50 nM) or NRX (100 nM) ( n = 4 per group). (C) Alcian blue staining of MSCs in micromass (scale bar = 1 mm). The blue stained area was extracted using ImageJ ( n = 4 per group). (D) The gene expression level of Sox9 in MSCs cultured in chondrogenic medium. Sox9 expression was upregulated by 7C, even in the absence of BMP-2 ( n = 3 per group). * p < 0.05, ** p < 0.01, *** p < 0.001 and **** p < 0.0001 and ns, not significant.
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    cd2665 (rarγ antagonists, cas 170355-78-9 - by Bioz Stars, 2026-08
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    rarγ-selective antagonist cd2665  (SRI International)
    90
    SRI International rarγ-selective antagonist cd2665
    Effect of <t>RARγ</t> agonist/antagonist on ATDC5 cells and MSCs. (A) Alcian blue staining of ATDC5 cells in micromass (scale bar = 1 mm). The blue stained area was extracted using ImageJ (version 1.52q, U. S. National Institutes of Health; https://imagej.nih.gov/ij/ ) ( n = 4 per group). (B) Quantitative RT-PCR analysis of ATDC5 cells cultured in chondrogenic medium supplemented with BMP-2 (20 ng/ml) and 7C (50 nM) or NRX (100 nM) ( n = 4 per group). (C) Alcian blue staining of MSCs in micromass (scale bar = 1 mm). The blue stained area was extracted using ImageJ ( n = 4 per group). (D) The gene expression level of Sox9 in MSCs cultured in chondrogenic medium. Sox9 expression was upregulated by 7C, even in the absence of BMP-2 ( n = 3 per group). * p < 0.05, ** p < 0.01, *** p < 0.001 and **** p < 0.0001 and ns, not significant.
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    Effect of RARγ agonist/antagonist on ATDC5 cells and MSCs. (A) Alcian blue staining of ATDC5 cells in micromass (scale bar = 1 mm). The blue stained area was extracted using ImageJ (version 1.52q, U. S. National Institutes of Health; https://imagej.nih.gov/ij/ ) ( n = 4 per group). (B) Quantitative RT-PCR analysis of ATDC5 cells cultured in chondrogenic medium supplemented with BMP-2 (20 ng/ml) and 7C (50 nM) or NRX (100 nM) ( n = 4 per group). (C) Alcian blue staining of MSCs in micromass (scale bar = 1 mm). The blue stained area was extracted using ImageJ ( n = 4 per group). (D) The gene expression level of Sox9 in MSCs cultured in chondrogenic medium. Sox9 expression was upregulated by 7C, even in the absence of BMP-2 ( n = 3 per group). * p < 0.05, ** p < 0.01, *** p < 0.001 and **** p < 0.0001 and ns, not significant.

    Journal: Frontiers in Cell and Developmental Biology

    Article Title: Selective Retinoic Acid Receptor γ Antagonist 7C is a Potent Enhancer of BMP-Induced Ectopic Endochondral Bone Formation

    doi: 10.3389/fcell.2022.802699

    Figure Lengend Snippet: Effect of RARγ agonist/antagonist on ATDC5 cells and MSCs. (A) Alcian blue staining of ATDC5 cells in micromass (scale bar = 1 mm). The blue stained area was extracted using ImageJ (version 1.52q, U. S. National Institutes of Health; https://imagej.nih.gov/ij/ ) ( n = 4 per group). (B) Quantitative RT-PCR analysis of ATDC5 cells cultured in chondrogenic medium supplemented with BMP-2 (20 ng/ml) and 7C (50 nM) or NRX (100 nM) ( n = 4 per group). (C) Alcian blue staining of MSCs in micromass (scale bar = 1 mm). The blue stained area was extracted using ImageJ ( n = 4 per group). (D) The gene expression level of Sox9 in MSCs cultured in chondrogenic medium. Sox9 expression was upregulated by 7C, even in the absence of BMP-2 ( n = 3 per group). * p < 0.05, ** p < 0.01, *** p < 0.001 and **** p < 0.0001 and ns, not significant.

    Article Snippet: CD2665 (RARγ antagonists, CAS 170355-78-9) and CD1530 (RARγ agonist, CAS:107,430-66-0) were purchased from Cayman Chemical Company (Ann Arbor, MI, United States).

    Techniques: Staining, Quantitative RT-PCR, Cell Culture, Expressing

    Effect of RARγ antagonists and agonists on BMP signaling. (A) Id1-luc reporter activity in ATDC5 cells treated with RARγ antagonists (CD2665 and 7C) with or without 10 ng/ml rhBMP-2. n = 4 per group. ** p < 0.01, *** p < 0.001, **** p < 0.0001, and ns, not significant. (B) Immunoblotting analysis with p-Smad1 antibody. The ATDC5 cells were treated with BMP-2 and increasing concentrations of RARγ antagonists (CD2665 and 7C) and RARγ agonists (NRX204647 and CD1530). The cell lysates were prepared 45 min after treatment and subjected to immunoblot analysis for p-Smad1 and GAPDH.

    Journal: Frontiers in Cell and Developmental Biology

    Article Title: Selective Retinoic Acid Receptor γ Antagonist 7C is a Potent Enhancer of BMP-Induced Ectopic Endochondral Bone Formation

    doi: 10.3389/fcell.2022.802699

    Figure Lengend Snippet: Effect of RARγ antagonists and agonists on BMP signaling. (A) Id1-luc reporter activity in ATDC5 cells treated with RARγ antagonists (CD2665 and 7C) with or without 10 ng/ml rhBMP-2. n = 4 per group. ** p < 0.01, *** p < 0.001, **** p < 0.0001, and ns, not significant. (B) Immunoblotting analysis with p-Smad1 antibody. The ATDC5 cells were treated with BMP-2 and increasing concentrations of RARγ antagonists (CD2665 and 7C) and RARγ agonists (NRX204647 and CD1530). The cell lysates were prepared 45 min after treatment and subjected to immunoblot analysis for p-Smad1 and GAPDH.

    Article Snippet: CD2665 (RARγ antagonists, CAS 170355-78-9) and CD1530 (RARγ agonist, CAS:107,430-66-0) were purchased from Cayman Chemical Company (Ann Arbor, MI, United States).

    Techniques: Activity Assay, Western Blot